S.E.M.I.: Side Effects May Include...

S.E.M.I.: Side Effects May Include...

Two Horn Unicorn · 2026

How you play it

2-4 players online

Online co-op · up to 4

What it does best

  • comedy

  • party

  • arcade

Look

Peek inside

S.E.M.I.: Side Effects May Include... gameplay 1S.E.M.I.: Side Effects May Include... gameplay 2S.E.M.I.: Side Effects May Include... gameplay 3S.E.M.I.: Side Effects May Include... gameplay 4S.E.M.I.: Side Effects May Include... gameplay 5

The setup

What you are walking into

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

Where it lives

PC (Microsoft Windows)

Genre

IndieHack and slash/Beat 'em upArcade

Vibe

ComedyPartyAction
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